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Listed in Category: Antibacterial medication

Augmentin 875 mg / 125 mg 14 tablets

Availability: In Stock

$39.00

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Active ingredients: Amoxicillin, Clavulanic Acid
Manufacturer: GlaxoSmithKline
Country of Origin: United Kingdom
Description: Antibiotic of a broad-spectrum penicillin group with a beta-lactamase inhibitor
Array

Trade names - Aclav, Alvonal, Amelock, Autarmin, Cax, Clavamox, Claver, CLAMP, Clavotrol BD, Claxy,Co-Symoxyl, Danoclav, Daxet, Enhancin, Fightox, Hibrid, Mox Clav, Moxlin CLV, Moxynic, Nacova, Novaclav, Rolab-Amoclav, Surpas, Warclav

Composition

amoxicillin (trihydrate)875 mg clavulanic acid (potassium salt)125 mg 

Pharmacological effects

Combined broad-spectrum antibiotic resistant to beta-lactamase containing amoxicillin and clavulanate acid. Amoxicillin - a semisynthetic broad-spectrum antibiotic active against many gram-positive and gram-negative microorganisms. The amoxicillin is exposed to destruction by beta-lactamases, so the spectrum of its antibacterial activity does not include microorganisms, producing beta-lactamases. Clavulanic acid beta - lactam compound, which possesses the ability to inactivate a wide range of betalactamases, enzymes that are normally produced by microorganisms resistant to penicillins and cephalosporins. The presence of clavulanic acid in the Augmentin protects amoxicillin from degradation by beta-lactamase enzymes and extends the range of its antibacterial activity with the inclusion of micro-organisms, usually resistant to other penicillins and cephalosporins. Augmentin® is active against aerobic gram-positive microorganisms: Bacillis anthracis*, Corynebacterium spp., Enterococcus faecalis*, Enterococcus faecium*, Listeria monocytogenes, Nocardia asteroides, Staphylococcus aureus*, coagulase-negative staphylococci (including Staphylococcus epidermidis), Streptococcus spp. (including Streptococcus agalactiae, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus viridans); gram-positive anaerobic bacteria: Clostridium spp. Peptococcus spp., Peptostreptococcus spp.; against gram-negative aerobic microorganisms: Bordetella pertussis, Brucella spp., Escherichia coli*, Gardnerella vaginalis, Haemophilus influenzae*, Helicobacter pylori, Klebsiella spp.*, Legionella spp. Moraxella catarrhalis* (Branhamella catarrhalis), Neisseria gonorrhoeae*, Neisseria meningitidis*, Pasteurella multocida, Proteus mirabilis* Proteus vulgaris*, Salmonella spp.*, Shigella spp.*, Vibrio cholerae, Yersinia enterocolitica*; against gram-negative anaerobic microorganisms: Bacteroides spp*. (including Bacteroides fragilis), Fusobacterium spp.*; against other microorganisms: Borrelia burgdorferi, Chlamydiae, Leptospira icterohaemorrhagiae, Treponema pallidum. *- some strains of these species of bacteria produce beta-lactamases, causing resistance to monotherapy with amoxicillin. Tablets of Augmentin containing 875 mg of amoxicillin and 125 mg clavulanic acid, represent a dosage form with delayed release, which differs from conventional tablets other pharmacokinetic parameters. This provides sensitivity to the drug those strains of Streptococcus pneumoniae whose resistance to amoxicillin is mediated by penicillin-binding proteins (penicillin-resistant strains of Streptococcus pneumoniae).

Indications Infectious

-inflammatory diseases caused by sensitive microorganisms: — infections of the upper respiratory tract and upper respiratory tract (including recurrent tonsillitis, sinusitis, otitis media), usually caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, Streptococcus pyogenes; — infections of the lower respiratory tract: acute exacerbations of chronic bronchitis, lobar pneumonia and bronchopneumonia, usually caused by Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis; — urinary tract infection: cystitis, urethritis, pyelonephritis, infections of the female genital organs, usually caused by species of the family Enterobacteriaceae (mostly Escherichia coli), Staphylococcus saprophyticus and species of the genus Enterococcus, as well as gonorrhea, called Neisseria gonorrhoeae; — infections of skin and soft tissue, usually caused by Staphylococcus aureus, Streptococcus pyogenes and Bacteroides species; infection bones and joints

Contraindications

— jaundice or abnormal liver function on the background of the use of Augmentin in anamnesis; — hypersensitivity to beta-lactam antibiotics (including penicillin and cephalosporins). Not recommended for use Augmentin® in case of suspected infectious mononucleosis, since in such cases, amoxicillin can cause skin rash, which makes diagnosis of the disease

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