Pharmachologic effect

Antibacterial agent for topical application in ophthalmology, sulfonamide derivative. Has a wide spectrum of antimicrobial action. Has a bacteriostatic effect. The mechanism of action is associated with competitive antagonism with PABA and competitive inhibition of dihydropteroate synthetase, which leads to a disruption in the synthesis of tetrahydrofolic acid necessary for the synthesis of purines and pyrimidines.

Sulfacetamide is active against Gram-positive and Gram-negative bacteria (including pathogenic cocci, Escherichia coli), Chlamydia spp., Actinomyces spp.

Indications

Purulent corneal ulcers, conjunctivitis, blepharitis, gonorrheal diseases of the eyes in newborns and adults, prevention of blenarea in newborns.