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pharmachologic effect
Combination drug for topical application in ophthalmology.
Neomycin has a bactericidal effect, disrupting the synthesis of the bacterial cell protein. It is active against Staphylococcus aureus, Corynebacterium diphteriae, Streptococcus viridans, Escherichia coli, Klesiella pneumoniae, Proteus vulgaris, Aerobacter aerogenes, Haemophillus influenzae.
The mechanism of action of polymyxin B is mainly due to blockade of the permeability of the cytoplasmic membrane of bacterial cells. It is active against Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Klesiella pneumoniae, Koch-Weeks bacillus.
Dexamethasone
GCS. Has anti-inflammatory, antiallergic and desensitizing effects. Has an antiexudative effect. Dexamethasone effectively suppresses inflammatory processes.
Combination of SCS with antibiotics allows to reduce the risk of development of the infectious process.
Indications
Infections of the eyes and its appendages:
- blepharitis;
- conjunctivitis;
- keratoconjunctivitis;
- keratitis;
- Iridocyclitis.
Prevention of postoperative infectious complications.