Pharmachologic effect

A broad-spectrum antimicrobial agent from the group of fluoroquinolones for topical application in ophthalmology. The bactericidal effect of ofloxacin is associated with the blockade of the DNA-gyrase enzyme in bacterial cells.

Highly active against most Gram-negative microorganisms: Escherichia coli, Salmonella spp., Proteus spp., Morganella morganii, Shigella spp., Klebsiella spp., Enterobacter spp., Serratia spp., Citrobacter spp., Yersinia spp., Providencia spp., Haemophilus influenzae, Neisseria gonorrhoeae, Neisseria meningitidis, Mycoplasma spp., Legionella pneumophila, Acinetobacter spp., Chlamydia spp.

It is active against some Gram-positive microorganisms, in particular Staphylococcus spp., Streptococcus spp.

Moderately sensitive to ofloxacin Enterococcus faecalis, Streptococcus pneumoniae, Pseudomonas spp.

Ofloksatsinu sensitive microorganisms that produce β-lactamase.

The drug is insensitive to anaerobic bacteria (except Bacteroides urealyticus).

Indications

Infectious-inflammatory diseases of the anterior part of the eye caused by microorganisms sensitive to ofloxacin:

- blepharitis;

- barley;

- conjunctivitis;

- Dacryocystitis;

- keratitis;

- corneal ulcer;

Chlamydial infection of the eyes.

Prevention and treatment of bacterial infections after eye injuries and surgical interventions.