pharmachologic effect

The histamine H1 receptor blocker, the cetirizine enantiomer, belongs to the group of competitive histamine antagonists. The affinity for histamine H1 receptors in levocetirizine is 2 times higher than in cetirizine.

Levocetirizine influences the histamine-dependent stage of allergic reactions, and also reduces the migration of eosinophils, reduces vascular permeability, and limits the release of inflammatory mediators. Prevents development and facilitates the course of allergic reactions, has antiexudative, antipruritic effect, practically does not have anticholinergic and antiserotonin action. In therapeutic doses, it practically does not have a sedative effect.

Indications

Symptomatic therapy of allergic diseases and conditions:

- All-the-year-round (persistent) and seasonal (intermittent) allergic rhinitis and allergic conjunctivitis (itching, sneezing, rhinorrhea, lacrimation, congestion hyperemia, nasal congestion);

- Pollinosis (hay fever);

- urticaria (including chronic idiopathic urticaria);

- Quincke's edema;

- other allergic dermatoses, accompanied by itching and rashes.