Pharmacological action

The drug for the treatment of nicotine addiction, n-holinomimetik. The alkaloid cytisine is an active substance of the drug, it has an n-cholinomimetic effect. Its effects are expressed in the following: it excites the ganglia of the autonomic nervous system, reflexively stimulates breathing, causes adrenaline release from the adrenal medulla, raises blood pressure.

With a close resemblance to the mechanism of action of nicotine, cytisine has a much lower toxicity and a wider therapeutic index. Cytisine competitively suppresses the interaction of nicotine with the corresponding receptors, which leads to a gradual decrease and disappearance of nicotine (tobacco) dependence.

Indications

- treatment of nicotine addiction (to facilitate quitting).

Physical and psychological dependence on nicotine is considered a specific type of disease, which leads to the inability to abstain from smoking, even with an understanding of its negative effects.