Pharmacological action

Octagam contains mainly immunoglobulins of class G - antibodies to pathogens of various infections. The distribution of subclasses of immunoglobulin G (IgG) in the preparation is the same as in natural plasma and has all the characteristics characteristic of a healthy person. Effective doses of the drug can restore a low level of IgG to its normal level. IgG molecules are not subject to change due to chemical or enzymatic action. The activity of antibodies is completely preserved.

Octagam® contains no more than 3% of polymers, the content of monomers and dimers is not less than 90%.

Indications

Substitution therapy:

- Syndromes of primary immunodeficiency, incl. Congenital agammaglobulinemia and hypogammaglobulinemia, unclassifiable variable immunodeficiency, severe combined immunodeficiency, Wiskott-Aldrich syndrome;

- Myeloma or chronic lymphatic leukemia with severe secondary hypogammaglobulinemia and recurrent infections;

- recurrent infections in children with congenital HIV infection.

Immunomodulatory therapy:

- idiopathic thrombocytopenic purpura in adults and children with a high risk of bleeding or before surgery to correct the number of platelets;

- Guillain-Barre syndrome;

- Kawasaki's disease;

- bone marrow transplantation.