pharmachologic effect
Miorelaxant of central action; agonist of GABAB receptors. Reducing the excitability of the end sections of the afferent sensitive fibers and suppressing the intermediate neurons, inhibits the mono- and polysynaptic transmission of nerve impulses; reduces the preliminary stress of the muscle spindles. Does not affect the transfer of impulses in neuromuscular synapses. With neurological diseases accompanied by spasticity of skeletal muscles, it alleviates painful spasms and clonic convulsions. Increases the volume of movement in the joints, facilitates the conduct of passive and active kinesitherapy (physical exercises, massage, manual therapy).

Indications
Increased muscle tone with:

- Multiple sclerosis;

- diseases of the spinal cord (tumors, syringomyelia, motor neuron diseases, trauma, myelitis);

- cerebrovascular diseases;

- cerebral palsy;

- Meningitis;

- craniocerebral trauma.