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Listed in Category: Nervous system

Tegretol CR 400 mg 30 tablets

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$31.00

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Active substances: Carbamazepine
Manufacturer: Novartis Pharma
Country of origin: Italy
General description: anticonvulsants
Array

pharmachologic effect

Antiepileptic agent, derivative of tricyclic iminostilbene. It is believed that anticonvulsant action is associated with a decrease in the ability of neurons to maintain a high frequency of development of repeated action potentials through inactivation of sodium channels. In addition, it seems that inhibition of the release of neurotransmitters by blocking the presynaptic sodium channels and the development of action potentials, which in turn reduces the synaptic transmission, is important.

Has a moderate antimanic, antipsychotic effect, as well as analgesic effect with neurogenic pain. The mechanisms of action may involve GABA receptors, which may be associated with calcium channels; Also, apparently, the effect of carbamazepine on the systems of neurotransmitter modulators is important.

The antidiuretic effect of carbamazepine may be associated with a hypothalamic effect on the osmoreceptors, which is mediated through the secretion of ADH, and is also due to direct action on the renal tubules.

Indications

Epilepsy: large, focal, mixed (including large and focal) epileptic seizures. Pain syndrome predominantly of a neurogenic genesis, incl. Essential neuralgia of the trigeminal nerve, trigeminal neuralgia with multiple sclerosis, essential glossopharyngeal neuralgia. Prevention of seizures in alcohol withdrawal syndrome. Affective and schizoaffective psychosis (as a means of prevention). Diabetic neuropathy with pain syndrome. Non-diabetes mellitus of central genesis, polyuria and polydipsia of neurohormonal nature.

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