Dosage form

nasal drops 0.1%

Composition

metilparagidroksibenzoat (Nipagina) – 1 g, purified water to 1 L.

Pharmacological action

Semax nasal drops 0.1% – the original synthetic peptide preparation, which is an analog of a fragment of adrenocorticotropic hormone (АКТГ4-10) (methionyl-glutamyl-histidyl-phenylalanyl-shed-glycyl-Proline) is completely devoid of hormonal activity. All amino acids are L-forms.

Testimony

Intellectual-mental disorders in vascular lesions of the brain, conditions after craniocerebral trauma, neurosurgical operations and anesthesia, discirkulatornaya encephalopathy, transient disorders of cerebral circulation (TIA), as well as neurotic disorders of various origins, including after ionizing radiation, the recovery period after a stroke.To enhance the adaptive capacity of the human body in extreme situations, prevention of mental fatigue during monotonic operator activity in the most intense periods of work in a stressful environment.

In ophthalmology Semax is used in atrophy of the optic nerve, neuritis inflammatory, toxic-allergic etiology

In Pediatrics: as nootropic agents in children aged 5 years in the treatment of minimal brain dysfunction (including ADHD – attention deficit disorder with hyperactivity)

Contraindications

Hypersensitivity to the drug. Children up to 5 years. Pregnancy, lactation, acute psychosis, disorders accompanied by anxiety, convulsions in history.

Drug interactions

Pharmaceutical. The chemical structure of the drug availability chemically incompatible combinations are not expected: the drug is rapidly destroyed in the gastrointestinal tract is not received.

The pharmacokinetic. Considering the chemical structure of the drug (heptapeptide - a synthetic analogue of adrenocorticotropic hormone, completely devoid of hormonal activity), the speed of suction and speed of the blood flow, as well as intranasal route of administration, the influence of other drugs on the pharmacokinetic parameters Semax nasal drops 0.1% is not expected. Given the route of administration Semax nasal drops 0.1% (intranasal) undesirable introduction means having local vasoconstrictor effect when administered intranasally.