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Listed in Category: Nervous system

Mydocalm 50 mg 30 tablets

Availability: In Stock



Active substances: tolperisone
Producer: Gedeon Richter of
Country of origin: Russia
General description: Muscle relaxants centrally acting

pharmachologic effect

Miorelaxant of central action. The mechanism of action is not fully understood. Has a membrane-stabilizing, local anesthetic effect, inhibits the conductivity of pulses in the primary afferent fibers and motor neurons, which leads to blockage of spinal mono- and polysynaptic reflexes. It also probably inhibits the release of mediators again by inhibiting the entry of Ca2 + into the synapses. In the brain stem eliminates the ease of carrying out excitation along the reticulospinal path. It enhances peripheral blood flow regardless of the influence of the central nervous system. In the development of this effect, the weak spasmolytic and adrenoblocking effect of tolperisone plays a role.


- treatment of pathologically increased tone and spasms of the striated muscles resulting from organic diseases of the central nervous system (affection of pyramidal tracts, multiple sclerosis, cerebral stroke, myelopathy, encephalomyelitis);

- treatment of increased tonus and muscle spasms, muscle contractures accompanying diseases of the organs of motion (for example, spondylosis, spondyloarthrosis, cervical and lumbar syndromes, arthrosis of large joints);

- Restorative treatment after orthopedic and traumatological operations;

- in the combination therapy of obliterating vascular diseases (obliterating arteriosclerosis, diabetic angiopathy, thromboangiitis obliterans, Raynaud's disease, diffuse scleroderma);

- as part of a combination therapy of diseases arising from violations of vascular innervation (acrocyanosis, intermittent angioedema dysbasia);

- Little's disease (cerebral spastic paralysis) and other encephalopathies accompanied by muscular dystonia.

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