pharmachologic effect

A remedy for the treatment of dementia. It is a noncompetitive antagonist of glutamate NMDA-receptors (including in black substance), thereby reducing the excessive stimulating effect of cortical glutamate neurons on neostriatum, which develops against the background of insufficient dopamine excretion. Reducing the entry of Ca2 + into neurons, reduces the possibility of their destruction.

Has nootropic, cerebrozodilating, antihypoxic and psychostimulating action.

Improves weakened memory, increases the ability to concentrate, reduces fatigue and symptoms of depression, reduces spasticity of skeletal muscles, caused by diseases or brain damage.

Indications

Dementia of moderate and severe degree in Alzheimer's disease.