Dosage form

Tablets, film-coated greenish yellow round brilliant

Composition

deproteinized gemoderivat from the blood of calves 200 mg 

Excipients: magnesium stearate, povidone К90, talc, cellulose. 

Shell composition: acacia gum, wax mountain glycol, these phthalate, diethyl, dye quinoline yellow aluminium lacquer, macrogol 6000, povidone K30, sucrose, talc, titanium dioxide.

Pharmacological action

A drug that activates metabolism in tissues, reduces tissue hypoxia, improves trophic and stimulating the regeneration process. Represents gemoderivat which is prepared by dialysis and ultrafiltration (permeate compounds with a molecular weight less than 5000 daltons). 

Positively affects the transport and utilization of glucose stimulates oxygen consumption (which leads to stabilization of plasma membranes of cells during ischemia and reduced the formation of lactate) having thus anti-hypoxic action.

Actovegin® increases the concentration of ATP, ADP, phosphocreatine, and amino acids (glutamate, aspartate) and GABA. 

Actovegin effect begins to appear no later than 30 minutes after ingestion and reaches a maximum after an average of 3 hours (2-6 hours).

Testimony

in the complex therapy of metabolic and vascular disorders of the brain (the various forms of cerebrovascular insufficiency, dementia, craniocerebral injury);

— peripheral (arterial and venous) vascular disturbances and their consequence (angiopathy, trophic ulcers).

Contraindications

— hypersensitivity to the drug or to similar drugs.

With caution should designate product in heart failure II-III stage, pulmonary edema, oliguria, anuria, hyperhydration, during pregnancy and lactation.

Drug interactions

Drug interactions drug Actovegin® is not installed.