Dosage form
Tablets, film-coated
Composition
1 tab.

inosine 200 mg
Pharmacological action
Improves myocardial metabolism, has antihypoxic and antiarrhythmic effect. Increases the energy balance of the myocardium. Has a protective effect on renal ischemia during surgery.

Involved in the metabolism of glucose, increases the activity of some enzymes of the Krebs cycle. Stimulates the synthesis of nucleotides.
Pharmacokinetics
Inosine is well absorbed from the gastrointestinal tract. It is metabolized in the liver to form glucuronic acid and its subsequent oxidation. In small amounts excreted by the kidneys.

Testimony
Coronary artery disease, myocardial dystrophy, status post myocardial infarction, congenital and acquired heart defects, heart rhythm disturbances, especially when glycoside intoxication, myocarditis, dystrophic changes in myocardium after strenuous exercise and infectious diseases or due to endocrine disorders, hepatitis, cirrhosis, fatty liver, including caused by alcohol or drugs; prevention of leukopenia during radiation exposure; operations on isolated kidney (as a means of pharmacological protection in the temporary absence of blood circulation in the operated body).
Contraindications
Gout, hyperuricemia, hypersensitivity to inosine.