Pharmacological action

Meldonium is a structural analogue of gamma-butyrobetaine, a substance that is found in every cell of the human body.

Under conditions of increased stress, Mildronate® restores the balance between delivery and the need for cells in oxygen, eliminates the accumulation of toxic metabolic products in cells, protecting them from damage; has also a tonic effect. As a result of its use, the body acquires the ability to withstand the load and quickly restore energy reserves. Due to these properties, Mildronate® is used to treat various disorders of the cardiovascular system, blood supply to the brain, and to increase physical and mental performance. As a result of a decrease in the concentration of carnitine, gamma-butyrobetaine, which has vasodilating properties, is synthesized intensively.

In the case of acute ischemic myocardial damage, Mildronate® slows the formation of the necrotic zone, shortens the rehabilitation period. With heart failure increases myocardial contractility, increases exercise tolerance, reduces the incidence of angina attacks.

In acute and chronic ischemic disorders of cerebral circulation, Mildronate improves blood circulation in the ischemic focus, promotes redistribution of blood in favor of the ischemic site.

The drug eliminates functional disorders of the nervous system in patients with chronic alcoholism with withdrawal syndrome.

Indications

- in the complex therapy of IHD (angina pectoris, myocardial infarction);

- Chronic heart failure;

- dyshormonal cardiomyopathy;

- in the complex therapy of acute and chronic disorders of blood supply to the brain (stroke and cerebrovascular insufficiency);

- hemophthalmia and hemorrhages in the retina of various etiologies;

- thrombosis of the central vein of the retina and its branches;

- Retinopathy of various etiologies (diabetic, hypertensive);

- reduced working capacity;

- mental and physical overstrain (including athletes);

- Abstinence syndrome with chronic alcoholism (in combination with specific therapy of alcoholism).