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Listed in Category: Antiviral Medication

Acyclovir 400 mg 20 tablets

Availability: In Stock



Active ingredients: Acyclovir
Manufacturer: various options
Country of origin: Russia
General description: The antiviral agent

Acyclovir analogue with the same active substance Zovirax

pharmachologic effect

Antiviral drug, a synthetic analogue of acyclic purine nucleoside, which has a highly selective effect on herpes viruses. In infected cells containing viral thymidine kinase, phosphorylation and conversion to acyclovir monophosphate occurs. Under the influence of guanylyl cyclase acyclovir, monophosphate is converted to diphosphate and under the influence of several cellular enzymes - into triphosphate.

Acyclovirtriphosphate is inserted into the viral DNA chain and blocks its synthesis by competitive inhibition of the viral DNA polymerase. Specificity and very high selectivity of action are also due to its predominant accumulation in cells affected by the herpes virus.

Highly active against Herpes simplex virus type 1 and type 2; a virus that causes varicella and herpes zoster (Varicella zoster); the Epstein-Barr virus. Moderately active against cytomegalovirus.

When herpes prevents the formation of new elements, reduces the likelihood of cutaneous dissemination and visceral complications, accelerates the formation of crusts, reduces pain in the acute phase of herpes zoster.


- treatment of infections of the skin and mucous membranes caused by viruses Herpes simplex 1 and 2 types, both primary and secondary, including genital herpes;

- Prevention of exacerbations of recurrent infections caused by Herpes simplex viruses 1 and 2 types, in patients with normal immune status;

- prevention of primary and recurrent infections caused by Herpes simplex viruses 1 and 2 types, in patients with immunodeficiency;

- as part of complex therapy in patients with severe immunodeficiency: with HIV infection (stage AIDS, early clinical manifestations and a developed clinical picture) and in patients who underwent bone marrow transplantation;

- treatment of primary and recurrent infections caused by the virus Varicella zoster (chicken pox, shingles).

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