leaflet

 

Amoxicillin capsules, solid, 500 mg

Packing: 16 x 500mg

Manufacturer: Hemofarm

 

Please read this manual before you start taking this medicine.

Keep this leaflet. You may need to read it again.

If you have any questions, ask your doctor or pharmacist.

This medicine has been prescribed for you, and you should not pass it on to others. It may harm them, even if they have the same symptoms of the disease as you.

If any of the side effects gets serious, or if you notice any side effects not listed in

this booklet, please tell your doctor or pharmacist.

In this brochure:

1. What is the drug amoxicillin, and is intended

2. What you need to know before you take the medicine Amoxicillin

3. How to use the drug amoxicillin

4. Possible side effects

5. How to store medicine amoxicillin

6. Additional information

 

1 . WHAT IS THE MEDICINE AMOXICILLIN AND WHAT IT IS USED?

Amoxicillin is a broad spectrum antibiotic effects of penicillin. It is used to treat a large number of

bacterial infection, as well as to prevent infections following surgical procedures (e.g., extraction

teeth).

It can also be used as part of a combination therapy of peptic ulcer (gastric and duodenal ulcers

intestines).

 

2. What you should know before taking medicine AMOXICILLIN

Warn your doctor if you are taking other medicines, have a chronic disease, a metabolic disorder,

hypersensitivity to medicines or you have had an allergic reaction to some of them.

Amoxicillin drug should not be used if:

- You have an allergy to amoxicillin, penicillin or any of the excipients in the composition of the drug (see section

6.1)

- Have you ever had an allergic reaction to antibiotics.

When you take your medicine amoxicillin special care if:

- Suffering from infectious mononucleosis (a viral infection, the symptoms are sore throat, fever

(> 39ºC), fatigue, muscle pain and headache)

- Do you have a disorder of renal function

- Difficulty urinating

- Reception of a medicament for blood coagulation

In the case of laboratory testing for the presence of glucose in urine or functional

liver function tests (transaminases), tell your doctor that you are on treatment with amoxicillin.

Taking other medicines

Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including

those that can be bought without a prescription.

Be careful if you are taking the following medicines:

 probenecid or allopurinol (to treat gout)

 warfarin, acenocoumarol (blood thinners)

; • Oral contraceptives (birth control pills) because amoxicillin can reduce their effects. during

taking amoxicillin is necessary to use additional non-hormonal methods of contraception.

Taking medications amoxicillin with food and drink

The drug Amoxicillin is better to take at the beginning of a meal, or just before eating.

Administration of amoxicillin during pregnancy and breast-feeding

If you are pregnant, plan to become pregnant or if you are breast-feeding consult your doctor before you start using this drug.

The effect of amoxicillin dosage drive or operate machinery

Amoxicillin drug does not affect the ability to drive and use machines.

Important information about some of the ingredients amoxicillin

Amoxicillin capsules contain as excipients preparation of azo dyes, which can cause allergic reactions.

 

3. HOW TO TAKE AMOXICILLIN

Take this medicine in strict accordance with the doctor's instructions to determine the appropriate dose and duration

Treatment depends on the type, location and severity of the infection.

The drug is administered orally. Swallow capsule whole, with a sufficient amount of fluid in or just prior to the beginning

food. doses evenly throughout the day. The time period between receiving two doses not

must be at least 4 hours; Never take two doses of drug for 1 hour. The maximum recommended

The daily dose of 6 g (3 g, 2 times a day).

 

Usual dosage:

Children under 40 kg body weight, which can not swallow capsules:

All doses were adjusted according to the child's body weight in kilograms.

 Your doctor will advise you how to amoxicillin drug should be given to your child.

 usual dose is - 40 mg to 90 mg per kilogram of body weight per day, divided into two or three

dose.

Adults, elderly and children over 40 kg body weight:

The usual dose of 250 mg three times a day; in cases of severe infection can be increased to 500

mg, three times a day.

Severe or recurrent respiratory infections: 3 g (6 capsules of 500 mg) twice a day.

urinary tract infections, two 3 g times (6 capsules of 500 mg), the distance between the dose should be 10

12 hours.

Dental abscesses (infections of the teeth and below the gum line) twice at 3 g (6 capsules of 500 mg); Separation between doses

It should be 8 hours.

Gonorrhea (sexually transmitted diseases) 3 g (6 capsules in 500 mg) once.

Gastric ulcer or duodenal ulcer: 750 mg (three 250 mg capsules or one capsule of 500 mg plus one

250mg) and 1 g (2 capsules of 500 mg), 2 times a day for seven days, in combination therapy with

and another group of antibiotic preparation of proton pump inhibitors.

HIV infection during surgical procedures: the dose will vary depending on the type of operation

intervention.

Prior to treatment, the doctor or dentist will provide you with more information about the method of administration.

If impairment of renal function, your doctor will advise you to take a lower dose of the drug.

If you take more Amoxicillin medication than you should

If you take more dose than that recommended you or someone else accidentally took the drug,

immediately contact your doctor, pharmacist or the nearest hospital.

Common symptoms of overdose include nausea, vomiting and diarrhea. In applying the drug Amoxicillin can happen

crystalluria (appearance of crystals in the urine), which in some cases can lead to kidney

weak sides.

If you forget to take the medicine Amoxicillin

Never take a double dose to make up for the fact that you forgot to take medicine!

If you forget to take your medicine at the usual time, take your usual dose as soon as you remember, and then continue to the prescribed dosage. Keep in mind that this should be done at least 4 hours between

take two doses.

What happens if you stop taking the drug amoxicillin

Treatment should not be interrupted without consulting a doctor.

drug use and set in 2-3 days after removal of symptoms, in order to cause infection in

completely removed from the body. Otherwise, it may be a surge of infection.

Do not take amoxicillin for more than two weeks. If you still do not feel well, please contact

your doctor.

When long-term administration of the drug may develop candidiasis (a fungal infection that affects the

in the vagina, mouth, or skin); In this case, consult a doctor.

 

4 . POSSIBLE SIDE EFFECTS

Like all medicines, amoxicillin can cause side effects.

If, during the use of this medicine, if you notice any of the following side effects, stop using the product and immediately

consult a doctor (these side effects are very rare, occurring less than 1 in 10,000 patients

taking the drug):

- Allergic reactions such as itching and skin rash, swelling of the face, lips, tongue or other parts of the body, difficulty

breath. This can be serious and sometimes lead to death;

- Rash, hives, or bruising of the skin that occur as a result of inflammation of blood vessels

due to allergic reactions. These skin changes may be accompanied by joint pain and disorder

renal function;

- Delayed allergic reaction that can occur 7-12 days after the injection and may occur

rash, fever, joint pain and swollen lymph nodes (especially in the area of the armpit);

-skin reactions of erythema, which appears as a reddish-purple skin changes,

especially noticeable on the palms and soles of the feet, the islands, the sensitivity of the lips, eyelids and intimate area,

often accompanied by fatigue and fever;

- Other serious forms of skin allergic reactions: skin discoloration, bumps under the skin, blisters, pustules

(Tiny skin lesions with purulent contents), peeling, redness, pain, itching, and peeling of the skin, which can be

accompanied by fever, headache, and pain;

- High fever, chills, sore throat or other signs of infection or increased bleeding tendency, which

may be signs of blood disorders;

- Colitis (inflammation of the colon mucosa), whose symptoms include diarrhea (diarrhea), sometimes with traces of blood in

Chair, pain and fever;

- Severe hepatic events, which occur most frequently in patients on long-term therapy in elderly

people, and often are reversible. These symptoms may not occur during the treatment and until several weeks after

discontinuation of the drug. If you notice changes in skin redness, blistering, bruising, yellow

discoloration of the skin and / or whites of the eyes, dark-colored urine and lighter-colored stools, diarrhea with traces of blood in the stool,

consult a doctor immediately.

In the case of less serious forms of skin reactions, such as mild skin rash (round, rosy red spots)

Islands in the legs, arms, hands and feet (these reactions occur from time to time in the 1-10 1000

patients taking the drug), consult a doctor.

Other side effects:

- Frequently (1-10 in 100 patients taking the drug) in skin rash can occur during use of the drug,

nausea, diarrhea (diarrhea);

- Periodically (1-10 cases per 1000 patients taking the drug): vomiting;

- Very rare (less than 1 in 10,000 patients taking the drug): candidiasis (a fungal infection that affects

in the vagina, mouth or skin), renal failure, seizures (the most common in patients treated with

therapy with high doses of medication or those with impaired renal function), drowsiness, hyperactivity,

discoloration of the teeth (in children), which usually takes place after brushing, brownish, yellowish or

dark tongue color change, which can have a hairy appearance, anemia (low red blood cell count

whose symptoms are fatigue, headaches, shortness of breath, dizziness, pale or yellowish discoloration of the skin and

whites of the eyes), prolonged coagulation time, you should keep in mind if you are sick or you start a bloody nose.

In patients with reduced urine output crystalluria rarely (a phenomenon may occur

tiny crystals in the urine, which can be in the turbidity of urine or urine) and is recommended input

enough fluids to maintain an adequate process of urination and thus reduce the possibility of

appearance of the disease.

If you notice any symptoms that may be adverse drug reactions, and are not mentioned in this

leaflet, please tell your doctor or pharmacist.

 

5 . HOW TO STORE AMOXICILLIN

Keep out of the reach of children!

Shelf life:

Amoxicillin capsules, solid, 250 mg: 4 years.

Amoxicillin capsules, solid, 500 mg: 4 years.

The drug should not be used after the expiration date printed on the package.

The expiry date refers to the last day of that month.

Storage:

Amoxicillin capsules, hard, 250 mg: Do not store above 25 ° C in the original package in order to protect

from light and moisture.

Amoxicillin capsules, hard, 500 mg: Do not store above 25 ° C in the original package in order to protect

from light and moisture.

Medicines should not be disposed of down the drain or waste. Ask your pharmacist how to remove drugs

You do not need. These measures will help to protect the environment. Dispose of unused medicine in accordance

the applicable regulations.

 

6. ADDITIONAL INFORMATION

What preparation containing amoxicillin

Active ingredients:

amoxicillin capsules, solid, 250 mg:

1 capsule contains:

Amoxicillin 250 mg

(In the form of amoxicillin trihydrate)

amoxicillin capsules, solid, 500 mg:

1 capsule contains:

Amoxicillin 500 mg

(In the form of amoxicillin trihydrate)