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Listed in Category: Antifungal medication

Terbinafine 250 mg 14 tablets

Availability: In Stock

$45.00

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Active ingredients: Terbinafine
Manufacturer: various options
Country of origin: Russia
General description: Antifungal
Array

Terbinafine analogue with the same active substance LAMISIL

Dosage form

Tablets 

Composition

terbinafine hydrochloride 281.25 mg, that corresponds to the content of terbinafine 250 mg

Auxiliary substances: sodium starch of glycolate, cellulose microcrystalline, lactose, hypromellose (hydroxypropyl methylcellulose), magnesium stearate, silicon dioxide colloidal (Aerosil).

Pharmacological action

Antifungal agent, allilamin. It has a broad spectrum of antifungal activity.

Active against dermatophytes: Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton verrucosum, Trichophyton violaceum, Microsporum canis, Epidermophyton floccosum. In low concentrations has a fungicidal effect on dermatophytes, mould fungi (including Aspergillus, Cladosporium, Scopulariopsis brevicaulis) and certain dimorphic fungi. In yeast fungi of the genus Candida (mainly Candida albicans) and filamentous forms, depending on the species, the drug has fungicidal or fungistatic.

Termikon® violates the early stage of the biosynthesis of the main components of the cell membrane of the fungus ergosterol by inhibiting enzyme squalene epoxidase. This leads to a deficiency of ergosterol and to an intracellular accumulation of squalene, which causes cell death of the fungus. The action of terbinafine by inhibiting the enzyme squalene epoxidase, located on the cell membrane of the fungus.

If ingestion is not effective in the treatment of multi-colored lichen, called Pityrosporum orbiculare (Malassezia furfur).

 

 

Testimony

— mycosis of the scalp (trichophytosis, microsporia);

— mycoses of the skin and nails caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton verrucosum, Trichophyton violaceum, Microsporum canis, Microsporum gypseum and Epidermophyton floccosum;

— onychomycosis;

— heavy common dermatomycosis smooth skin of the trunk and extremities, requiring systemic treatment;

— candidiasis of skin and mucous membranes

Contraindications

— pregnancy;

— the period of breastfeeding;

— children up to age 3 years and children weighing up to 20 kg;

— hypersensitivity to the drug.

With caution the drug should be used orally for kidney and/or liver failure, alcoholism, oppression kostnomozgovy blood, tumors, metabolic diseases, occlusal diseases of blood vessels of the extremities.

 

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